SLSU-Sogod (Main) Campus. On July 7, 1969, Sogod National Trade School was created by virtue of Republic Act No. 4352, a vocational institution tasked to answer the problem of lack of manpower training for adults and out of school youths. Twelve years after, the school once again was converted into Southern Leyte School of Arts and Trade, this time transforming it into an institution of tertiary education. Republic Act 7930 was enacted by the Congress of the Philippines on March 1, 1995 further converting the school into a chartered state College and renamed it Southern Leyte State College of Science and Technology (SLSCST).

Republic Act 9261 which was enacted and approved by Congress and the Senate Republic of the Philippines on March 7, 2004, established the Southern Leyte State University by integrating the Southern Leyte State College of Science and Technology in the Municipality of Sogod and Tomas Oppus Normal College in the Municipality of Tomas Oppus. With this development, five higher education campuses were integrated to comprise the university since SLSCST has been made host to three other CHED-supervised institutions in October 1999. Thus. The Southern Leyte State University is composed of institutions known as the following: SLSU-Sogod (Main) Campus Sogod, Southern Leyte SLSU-Tomas Oppus Campus Tomas Oppus, Southern Leyte SLSU-Bontoc Campus Bontoc, Southern Leyte SLSU-San Juan Campus San Juan, Southern Leyte SLSU-Hinunangan Campus Hinunangan, Southern Leyte.

This 12-hectare facility is situated in Barangay San Roque (main mampus), seven hundred meters (700 meters) away from the town hall of Sogod. With the Phil-Japan Friendship Highway (now Daang Maharlika), Sogod is accessible to the College making it as the excellent center for quality and relevant education. It is seventy-two kilometers from the provincial capital, Maasin, 180 kms. from Tacloban City and is a port of call for boats from Manila, Mindanao and Cebu.